Parkinsonism after glycine‐derivate exposure
Identifieur interne : 004730 ( Main/Exploration ); précédent : 004729; suivant : 004731Parkinsonism after glycine‐derivate exposure
Auteurs : Egberto R. Barbosa [Brésil] ; Maria D. Leiros Da Costa [Brésil] ; Luiz A. Bacheschi [Brésil] ; Milberto Scaff [Brésil] ; Claudia C. Leite [Brésil]Source :
- Movement Disorders [ 0885-3185 ] ; 2001-05.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
- KwdEn :
- Antiparkinson Agents (therapeutic use), Benserazide (therapeutic use), Case study, Drug Therapy, Combination, Globus Pallidus (pathology), Glycine (analogs & derivatives), Glycine (poisoning), Glyphosate, Grey matter, Herbicide, Herbicides (poisoning), Human, Humans, Levodopa (therapeutic use), Magnetic Resonance Imaging, Male, Middle Aged, Nuclear magnetic resonance imaging, Pallidum, Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (drug therapy), Parkinson Disease, Secondary (pathology), Parkinsonism, Poisoning, Substantia Nigra (pathology), Video recording, Videotape Recording.
- MESH :
- chemical , analogs & derivatives : Glycine.
- chemical , poisoning : Glycine, Herbicides.
- chemical , therapeutic use : Antiparkinson Agents, Benserazide, Levodopa.
- chemically induced : Parkinson Disease, Secondary.
- drug therapy : Parkinson Disease, Secondary.
- pathology : Globus Pallidus, Parkinson Disease, Secondary, Substantia Nigra.
- Drug Therapy, Combination, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Videotape Recording.
Abstract
This 54‐year‐old man accidentally sprayed himself with the chemical agent glyphosate, a herbicide derived from the amino acid glycine. He developed disseminated skin lesions 6 hours after the accident. One month later, he developed a symmetrical parkinsonian syndrome. Two years after the initial exposure to glyphosate, magnetic resonance imaging revealed hyperintense signal in the globus pallidus and substantia nigra, bilaterally, on T2‐weighted images. Levodopa/benserazide 500/125 mg daily provided satisfactory clinical outcome.
Url:
DOI: 10.1002/mds.1105
Affiliations:
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Le document en format XML
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<term>Drug Therapy, Combination</term>
<term>Globus Pallidus (pathology)</term>
<term>Glycine (analogs & derivatives)</term>
<term>Glycine (poisoning)</term>
<term>Glyphosate</term>
<term>Grey matter</term>
<term>Herbicide</term>
<term>Herbicides (poisoning)</term>
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<term>Levodopa (therapeutic use)</term>
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<term>Middle Aged</term>
<term>Nuclear magnetic resonance imaging</term>
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<term>Parkinson Disease, Secondary (drug therapy)</term>
<term>Parkinson Disease, Secondary (pathology)</term>
<term>Parkinsonism</term>
<term>Poisoning</term>
<term>Substantia Nigra (pathology)</term>
<term>Video recording</term>
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<term>Substantia Nigra</term>
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<term>Magnetic Resonance Imaging</term>
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<front><div type="abstract" xml:lang="en">This 54‐year‐old man accidentally sprayed himself with the chemical agent glyphosate, a herbicide derived from the amino acid glycine. He developed disseminated skin lesions 6 hours after the accident. One month later, he developed a symmetrical parkinsonian syndrome. Two years after the initial exposure to glyphosate, magnetic resonance imaging revealed hyperintense signal in the globus pallidus and substantia nigra, bilaterally, on T2‐weighted images. Levodopa/benserazide 500/125 mg daily provided satisfactory clinical outcome.</div>
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